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Idiotypic profile of the response to phosphorylcholine induced in the absence of the homologous antigen

✍ Scribed by Salvatore Cammisuli; Humberto Cosenza

Publisher: John Wiley and Sons
Year: 1980
Tongue: English
Weight: 666 KB
Volume: 10
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.1830100414

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## Abstract (CBA/N × BALB/c)F~1~ hybrid male mice are unable to mount anti‐phosphorylcholine (PC) plaque‐forming cell (PFC) responses because they carry the CBA/N X‐linked immune defect of B lymphocyte differentiation. Transplantation of splenic B cells from BALB/c mice restores responsiveness to t