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Idiotype-mediated intervention in systemic lupus erythematosus

✍ Scribed by Zouali, Moncef; Diamond, Betty


Book ID
123092709
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
551 KB
Volume
3
Category
Article
ISSN
0896-8411

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Systemic lupus erythematosus (SLE) is regarded as a classical autoimmune disease. Despite this belief, no one has been able to induce the disease in naive animals, neither with DNA nor with anti-DNA antibodies. We report on the induction of SLE in BALB/c mice following immunization with a pathogenic