Idiotype-anti-idiotype hapten immunoassays: Assay for cotinine
โ Scribed by John J. Langone; Robert J. Bjercke
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 618 KB
- Volume
- 182
- Category
- Article
- ISSN
- 0003-2697
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The administration of xenogenic monoclonal antibodies (MAbs) leads in many cases to a host immune response represented by the generation of antibodies that can be directed against allotypic, isotypic, and idiotypic determinants present on the xenogeneic MAb. Anti-idiotypic antibodies (Ab2s) can be d
## ~~ Anti-idiotypic (Anti-Id) monoclonal antibodies (MoAbs) against anti-carcinoembryonic antigen (CEA) monoclonal antibody 563 (IgG1) were prepared and characterized. Five anti-Id MoAbs recognized the private idiotype of MoAb 563. ldiotype mapping suggested that MoAb 563 had at least three disti
## Abstract Antiโpโazophenylarsonate (antiโAr) antibodies arising in strain A mice immunized with keyhole limpet hemocyaninโAr have previously been shown to exhibit strong idiotypic crossโreactions. The appearance of the crossโreacting idiotype is suppressed by prior administration of antiidiotypic