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IDENTIFYING BMD-INDEPENDENT GENETIC LOCI FOR BONE STRUCTURE AND STRENGTH IN THE MOUSE

✍ Scribed by Kevin S. Mader; Philipp Schneider; Davide Ruffoni; Thomas Kohler; Leah Rae Donahue; Ralph Müller; Marco Stampanoni

Book ID
117135893
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
164 KB
Volume
45
Category
Article
ISSN
0021-9290

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Bone mineral density (BMD) is a heritable trait, and in mice, over 100 quantitative trait loci (QTLs) have been reported, but candidate genes have been identified for only a small percentage. Persistent errors in the mouse genetic map have negatively affected QTL localization, spurring the developme