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Genetic Hypercalciuric Stone-Forming Rats Have a Primary Decrease in BMD and Strength

✍ Scribed by Marc Grynpas; Stephen Waldman; Douglas Holmyard; David A Bushinsky


Book ID
111485729
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
588 KB
Volume
24
Category
Article
ISSN
0884-0431

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## Abstract We have bred a strain of rats to maximize urine (u) calcium (Ca) excretion and model hypercalciuric nephrolithiasis. These genetic hypercalciuric stone‐forming (GHS) rats excrete more uCa than control Sprague‐Dawley rats, uniformly form kidney stones, and similar to patients, demonstrat