✦ LIBER ✦

Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist

✍ Scribed by Jun Chiba; Nobuo Machinaga; Tohru Takashi; Akio Ejima; Gensuke Takayama; Mika Yokoyama; Atsushi Nakayama; John J. Baldwin; Edward McDonald; Kurt W. Saionz; Robert Swanson; Zahid Hussain; Angela Wong

Book ID: 108073495
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 294 KB
Volume: 15
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2004.10.041

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Corrigendum to “Identified a morpholinyl

Corrigendum to “Identified a morpholinyl-4-piperidinylacetic acid derivatives as a potent oral active VLA-4 antagonist”: [Bioorg. Med. Chem. Lett. 15 (1) (2005) 41]

✍ Jun Chiba; Nobuo Machinaga; Tohru Takashi; Akio Ejima; Gensuke Takayama; Mika Yo 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 52 KB

4-(Pyrrolidinyl)methoxybenzoic Acid Deri

4-(Pyrrolidinyl)methoxybenzoic Acid Derivatives as a Potent, Orally Active VLA-4 Antagonist.

✍ Jun Chiba; et al. et al. 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 15 KB 👁 1 views

ChemInform Abstract: N-Acyl-L-phenylalan

ChemInform Abstract: N-Acyl-L-phenylalanine Derivatives as Potent VLA-4 Antagonists that Mimic a Cyclic Peptide Conformation.

✍ Li Chen; Jefferson Tilley; Richard V. Trilles; Weiya Yun; David Fry; Charles Coo 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

Identification of trans-4-[1-[[7-fluoro-

Identification of trans-4-[1-[[7-fluoro-2-(1-methyl-3-indolyl)-6-benzoxazolyl]acetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid as a potent, orally active VLA-4 antagonist

✍ Masaki Setoguchi; Shin Iimura; Yuuichi Sugimoto; Yoshiyuki Yoneda; Jun Chiba; To 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 714 KB

New process for the synthesis of imidazo

New process for the synthesis of imidazo[4,5-b]pyridine derivatives as potent orally active thromboxane a2 receptor antagonists

✍ E. Nicolaï; S. Claude; J. M. Teulon 📂 Article 📅 1994 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 194 KB

Acidic biphenyl derivatives: Synthesis a

Acidic biphenyl derivatives: Synthesis and biological activity of a new series of potent 5-HT4 receptor antagonists

✍ Brudeli, Bjarne; Andressen, Kjetil Wessel; Moltzau, Lise Román; Nilsen, Nils Ola 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 960 KB