Identification of the Sites of Hydroxyl Radical Reaction with Peptides by Hydrogen/Deuterium Exchange: Prevalence of Reactions with the Side Chains †
✍ Scribed by Goshe, Michael B.; Chen, Yong Hong; Anderson, Vernon E.
- Book ID
- 127225872
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 199 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0006-2960
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The reactions of HI with OH and NO3 have been studied in discharge-flow reactors coupled to EPR and mass spectrometry for analysis, The rate constants for the reactions HI+OH+H20 t I (1) and HI t NO3 +HNO, t I (2) were determined al 298 K: k,=(3.3+0.2)xlO-" and kz = (2.5f0.8) X 10 --IS cm3 molecule-
Gas-phase noncovalently bound complexes are probed by hydrogen/deuterium exchange. The complexes, composed of a protonated amino acid and a monosaccharide, are investigated to observe the effects of complexation on the rates of exchange. Rate constants are determined and compared for complexed and u