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Identification of the Principal Aflatoxin B1-DNA Adduct Formed in vivo in Rat Liver

✍ Scribed by R. G. Croy, J. M. Essigmann, V. N. Reinhold and G. N. Wogan

Book ID
123655060
Publisher
National Academy of Sciences
Year
1978
Tongue
English
Weight
887 KB
Volume
75
Category
Article
ISSN
0027-8424

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An immunoslot blotting (ISB) method for quantitating aflatoxin B1-DNA adduct levels has been developed and used to examine the relationship between dose and hepatic aflatoxin B1-DNA adduct levels in rats fed aflatoxin B1 (AFB1) in the diet at dose levels of between 0.5 and 10 micrograms/kg/day. The