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Identification of the Essential Cysteinyl Residue Located in the Active Site of Human PhenylethanolamineN-Methyltransferase

✍ Scribed by Norio Kaneda; Kiyomi Hikita; Yoriko Naruse; Taeko Fukuo; Kenichiro Matsubara; Toshiharu Nagatsu


Book ID
115582534
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
194 KB
Volume
249
Category
Article
ISSN
0006-291X

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The involvement of a histidyl residue in the binding or translocation step was investigated in the malate carrier at the tonoplast of Catharanthus roseus cells. The transport rate was strongly stimulated when the pH of the incubation medium was decreased from pH 7.0 to 5.0. The histidine-specific re