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Identification of the 37-kd rat liver protein that forms an acetaldehyde adduct in vivo as delta 4-3-ketosteroid 5 beta-reductase

โœ Scribed by Y Zhu; MJ Fillenwarth; D Crabb; L Lumeng; RC Lin


Book ID
118686087
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
354 KB
Volume
23
Category
Article
ISSN
0270-9139

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Identification of the 37-kd rat liver pr
โœ Y Zhu; M J Fillenwarth; D Crabb; L Lumeng; R C Lin ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 352 KB

After alcohol ingestion, ethanol is oxidized to acetal-Acetaldehyde, the first product of alcohol metabolism, is highly reactive. Several proteins have been shown to dehyde in the liver mainly by the action of alcohol dehybe covalently modified by acetaldehyde in vivo. We have drogenase 1 and, on pr