## Abstract Transforming growth factorβΞ²1 (TGFβΞ²1) is a crucial molecule for stimulation of breast cancer invasion and formation of bone metastases. The molecular mechanisms of how TGFβΞ²1 mediates these effects have yet to be completely determined. We have found that activating transcription factor
β¦ LIBER β¦
Identification of target genes for EWS/ATF-1 chimeric transcription factor
β Scribed by Jishage, Miki; Fujino, Takashi; Yamazaki, Yukari; Kuroda, Hiroshi; Nakamura, Takuro
- Book ID
- 110067203
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 447 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0950-9232
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We report a new case of clear cell sarcoma (CCS) harboring the t(12;22)(q13;q12). Reverse transcription-polymerase chain reaction (RT-PCR) analysis revealed the presence of a chimeric transcript between the EWS and ATF1 genes, both in primary and metastatic tissue. Sequencing studies disclosed an in