Somatic mutations and germline sequence
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Alexandra E. Gylfe; Johanna Sirkiä; Manuel Ahlsten; Heikki Järvinen; Jukka-Pekka
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Article
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2010
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John Wiley and Sons
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French
⚖ 204 KB
👁 1 views
## Abstract It is estimated that up to 35% of colorectal cancers (CRC) can be explained by hereditary factors. However, genes predisposing to highly penetrant CRC syndromes account for only a small fraction of all cases. Thus, most CRCs still remain molecularly unexplained. A recent systematic sequ