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Identification of Protein Substrates for Transglutaminase in Caenorhabditis elegans

✍ Scribed by András Mádi; Zoltán Kele; Tamás Janáky; Mária Punyiczki; László Fésüs

Book ID
115587945
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
141 KB
Volume
283
Category
Article
ISSN
0006-291X

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## Abstract Infantile neuronal ceroid lipofuscinosis (INCL; Batten disease) is a severe neurodegenerative disorder of childhood characterized by the accumulation of autofluorescent storage material in lysosomes. It is caused by mutation of the __CLN1/PPT1__ gene, which encodes the lysosomal enzyme