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Identification of presynaptic 5-HT1autoreceptors in pig brain cortex synaptosomes and slices

✍ Scribed by K. Fink; E. Schlicker; R. Betz; M. Göthert


Book ID
112275318
Publisher
Springer-Verlag
Year
1988
Tongue
English
Weight
541 KB
Volume
338
Category
Article
ISSN
0028-1298

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✍ K. Fink; M. Göthert; J. Zentner 📂 Article 📅 1995 🏛 Springer-Verlag 🌐 English ⚖ 410 KB

Human cerebral cortical synaptosomes were used to determine the 5-hydroxytryptamine (5-HT) receptor subtype to which the inhibitory presynaptic 5-HT autoreceptor belongs. The synaptosomes preincubated with [3H~5-HT were superfused and tritium overflow was stimulated by high K +. The K +-evoked triti