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Identification of Novel Pleckstrin Homology (PH) Domains Provides a Hypothesis for PH Domain Function

✍ Scribed by G. Shaw


Book ID
115573539
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
481 KB
Volume
195
Category
Article
ISSN
0006-291X

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Identification of a hyaluronic acid (HA)
✍ C.A. Vines; M.W. Li; X. Deng; A.I. Yudin; G.N. Cherr; J.W. Overstreet πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 213 KB

## Abstract The macaque sperm surface protein PH‐20 is a hyaluronidase, but it also interacts with hyaluronic acid (HA) to increase internal calcium (β€Š[Ca^2+^]~i~β€Š) in the sperm cell. A region of the PH‐20 molecule, termed Peptide 2 (aa 205–235), has amino acid charge homology with other HA binding