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Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

โœ Scribed by Isakoff, Steven J.; Cardozo, Tim; Andreev, Julian; Li, Zhai; Ferguson, Kathryn M.; Abagyan, Ruben; Lemmon, Mark A.; Aronheim, Ami; Skolnik, Edward Y.


Book ID
111745642
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
668 KB
Volume
17
Category
Article
ISSN
0261-4189

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## Abstract Sox2 and Octโ€3/4 function as master regulators during mammalian embryogenesis, where they are believed to regulate a critical gene regulatory network by cooperatively binding to DNA regulatory regions composed of adjacent HMG and POU motifs (HMG/POU cassettes). Previous studies have ide