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Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas

✍ Scribed by Geurts, Jan MW; Schoenmakers, Eric FPM; Röijer, Eva; Aström, Anna-Karin; Stenman, Göran; van de Ven, Wim JM

Book ID: 110061166
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 625 KB
Volume: 16
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1201609

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A subgroup of pleomorphic adenomas of the salivary glands is characterized by translocations involving chromosome 8, with consistent breakpoints at 8q 12. As part of a positional cloning effort to isolate the gene(s) affected by these translocations we now report the mapping of the 8q I 2 breakpoint