## Abstract Mammaglobin‐A is highly overexpressed in breast cancer cell lines and primary breast tumors. This pattern of expression is restricted to mammary epithelium and metastatic breast tumors. Thus, mammaglobin‐A‐specific T cell immune responses may provide an important approach for the design
✦ LIBER ✦
Identification of HLA-A24-restricted CD8+ cytotoxic T-cell epitopes derived from mammaglobin-A, a human breast cancer–associated antigen
✍ Scribed by Venkataswarup Tiriveedhi; Nayan J. Sarma; Vijay Subramanian; Timothy P. Fleming; William E. Gillanders; Thallachallour Mohanakumar
- Book ID
- 116533486
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 967 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0198-8859
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Previous studies have shown that self-antigens overexpressed in malignant tissue can provide a basis for a tumorspecific immune response. The mucin MUC2 is strongly overexpressed in all mucinous tumors of colon, breast, ovary and pancreas. In the corresponding normal tissue it is either not expresse