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Identification of hereditary pancreatitis mutation in three WV families

✍ Scribed by Elitsur, Y.; Chertow, BC.; Jewell, RD.; Finver, SN.; Primerano, DA.


Book ID
122781364
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
161 KB
Volume
114
Category
Article
ISSN
0016-5085

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Mutations of the cationic trypsinogen in
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Hereditary pancreatitis (OMIM 167800) is thought to be associated with a mutation of the exon 3 of cationic trypsinogen (Nature Genet (1996): 14:141-145). This paper reports sequence data of two independent families suffering from this disease. PCR amplificates from leukocyte or buccal swab DNA show