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Identification of HER2/neu-Derived Peptides Capable of Inducing both Cellular and Humoral Immune Responses in HLA-A24 Positive Breast Cancer Patients

โœ Scribed by Koichi Azuma; Shigeki Shichijo; Hiroki Shomura; Satoko Matsueda; Teruhiko Fujii; Kyogo Itoh


Book ID
111575075
Publisher
Springer US
Year
2004
Tongue
English
Weight
473 KB
Volume
86
Category
Article
ISSN
0167-6806

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Identification of Lck-derived peptides c
โœ Nobue Imai; Nanae Harashima; Masaaki Ito; Yoshiaki Miyagi; Mamoru Harada; Akira ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 132 KB ๐Ÿ‘ 1 views

The Lck protein (p56 lck ), a src family tyrosine kinase essential for T cell development and function, is aberrantly expressed in various types of cancers. We revealed recently that Lck can be a tumor antigen recognized by HLA-A24restricted and tumor-specific cytotoxic T lymphocytes (CTLs) of cance