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Identification of heat shock protein 60 as the regulator of the hypoxia-inducible factor subunit HIF-1α

✍ Scribed by Ban, Hyun Seung (author);Shimizu, Kazuki (author);Minegishi, Hidemitsu (author);Nakamura, Hiroyuki (author)


Book ID
120394254
Publisher
Walter de Gruyter GmbH
Year
2012
Tongue
English
Weight
744 KB
Volume
84
Category
Article
ISSN
0033-4545

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Identification of heat shock protein 60
✍ Ban, Hyun Seung (author);Shimizu, Kazuki (author);Minegishi, Hidemitsu (author); 📂 Article 📅 2012 🏛 Walter de Gruyter GmbH 🌐 English ⚖ 744 KB

The hypoxia-inducible factor (HIF) takes part in transcriptional activation of hypoxia-responsive genes such as vascular endothelial growth factor (VEGF), insulin-like growth factor, and inducible nitric oxide synthase. Since VEGF plays an important role in pathological angiogenesis such as tumor gr