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Identification of genes influencing synthetic lethality of genetic and epigenetic alterations in translation termination factors in yeast

✍ Scribed by D. A. Kiktev; Y. O. Chernoff; A. V. Archipenko; G. A. Zhouravleva


Book ID
111470172
Publisher
SP MAIK Nauka/Interperiodica
Year
2011
Tongue
English
Weight
205 KB
Volume
438
Category
Article
ISSN
1607-6729

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## Abstract The __SMARCA4__/__BRG1__ gene product is a component of the SWI‐SNF chromatin‐remodeling complex and regulates gene expression by disrupting histone‐DNA contacts in an ATP‐dependent manner. Inactivating mutations of the __SMARCA4__ gene, on chromosome arm 19p, are present in several hum