Genetic and Epigenetic screening for gen
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Pedro P. Medina; Julian Carretero; Mario F. Fraga; Manel Esteller; David Sidrans
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Article
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2004
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John Wiley and Sons
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English
⚖ 383 KB
## Abstract The __SMARCA4__/__BRG1__ gene product is a component of the SWI‐SNF chromatin‐remodeling complex and regulates gene expression by disrupting histone‐DNA contacts in an ATP‐dependent manner. Inactivating mutations of the __SMARCA4__ gene, on chromosome arm 19p, are present in several hum