Identification of Functional Human Splenic Memory B Cells by Expression of CD148 and CD27
β Scribed by Tangye, S. G.; Liu, Y.-J.; Aversa, G.; Phillips, J. H.; de Vries, J. E.
- Book ID
- 126899359
- Publisher
- Rockefeller University Press.
- Year
- 1998
- Tongue
- English
- Weight
- 524 KB
- Volume
- 188
- Category
- Article
- ISSN
- 0022-1007
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In this study the mode of expression of CD5 by human tonsillar CD5-B cells after stimulation with different agents was investigated. Resting B cells were separated into CD5+ and CD5cells and the two cell fractions exposed to phorbol 12-myristate 13-acetate (PMA). CD5-B cells expressed CD5 and maximu
## Abstract ## Background Differences between human and murine B cells exist at all stages of Bβcell development, including the stage of memory Bβcell formation. B cells in mice are identified with the panβBβcellβspecific CD45 isoform, B220. In initial studies in humans, it appeared that B220 expr