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Identification of dynorphin 1–8 in human placenta by mass spectrometry

✍ Scribed by Mahmoud S. Ahmed; Laura W. Randall; Baha Sibai; Chhabil Dass; Genevieve Fridland; Dominic M. Desiderio; Emirgul Tolun

Book ID
118342180
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
564 KB
Volume
40
Category
Article
ISSN
0024-3205

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Synaptic metabolism of the endogenous opioid octapeptide dynorphin (Dyn) A (1-8) (Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile) was studied in vitro upon its incubation with synaptosomes and with synaptosomal plasma membranes isolated from rat brain tissue. Electrospray ionization (ESI) and tandem mass spectrome