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Identification of Differentially Expressed Genes in Lung Tissues of Nickel-Exposed Rats Using Suppression Subtractive Hybridization

✍ Scribed by Jing Zhang; Jun Zhang; Yingying Fan; Lihong Liu; Mengjie Li; Yang Zhou; Zhihua Shao; Hongjun Shi; Ying Wang

Book ID: 107567126
Publisher: Humana Press Inc
Year: 2010
Tongue: English
Weight: 315 KB
Volume: 143
Category: Article
ISSN: 0163-4984
DOI: 10.1007/s12011-010-8898-4

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## Abstract To identify differentially expressed genes in human HCC in China, we applied a modified SSH method for cDNA subtraction. Such modification has made the method more effective for subtraction. We have obtained 36 and 24 differentially expressed cDNA fragments after modified SSH from 4 pai