Single-Nucleotide Polymorphism Analysis
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Afshin Ahmadian; Baback Gharizadeh; Anna C. Gustafsson; Fredrik Sterky; PΓ₯l NyrΓ©
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Article
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2000
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Elsevier Science
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English
β 129 KB
There is a growing demand for high-throughput methods for analysis of single-nucleotide polymorphic (SNP) positions. Here, we have evaluated a novel sequencing approach, pyrosequencing, for such purposes. Pyrosequencing is a sequencing-by-synthesis method in which a cascade of enzymatic reactions yi