## Communicated by Ann-Christine Syvanen Association screening involving numerous genetic markers is facilitated by the analysis of pooled DNA samples rather than individual samples. Several genotyping methods have shown high accuracy and precision of allele frequency estimation in pools. Here, we
β¦ LIBER β¦
Estimation of single nucleotide polymorphism allele frequency in DNA pools by using Pyrosequencing
β Scribed by Jonathan D. Gruber; Peter B. Colligan; Johanna K. Wolford
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 81 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0340-6717
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One of the major challenges in the near future is the identification of genes that contribute to complex disorders. Large scale association studies that utilize a dense map of single nucleotide polymorphisms (SNPs) have been considered as a valuable tool for this purpose. However, genome-wide screen