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Identification of Cell Binding Sites in the Laminin α5-Chain G Domain

✍ Scribed by Masayoshi Makino; Ikuko Okazaki; Shingo Kasai; Norio Nishi; Maria Bougaeva; Benjamin S. Weeks; Akira Otaka; Peter K. Nielsen; Yoshihiko Yamada; Motoyoshi Nomizu


Book ID
115604297
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
291 KB
Volume
277
Category
Article
ISSN
0014-4827

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The carboxy-terminal globular domain (G-domain) of the laminin ␣1 chain has been shown to promote heparin binding, cell adhesion, and neurite outgrowth. In this study, we defined the potential sequences originating from the G-domain of laminin ␣1 chain which possess these functional activities. A se