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Identification of caffeine and its metabolites in human urine extracts by electron impact ionization tandem mass spectrometry

✍ Scribed by A. Liguori; P. Mascaro; B. Porcelli; G. Sindona; N. Uccella

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 422 KB
Volume: 26
Category: Article
ISSN: 1076-5174
DOI: 10.1002/oms.1210260613

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✦ Synopsis

Electron impact ionized purine bases such as caffeine and its metabolites (theophylline, theobromine, paraxanthine, 1-metbylxanthiw, 3methylxnntbine and 7-metbylxanthiw) were characterized by tandem mass spectrometry. The direct analysis of human urinary extracts by tandem mass spectrometry allows the unambiguous identification of caffeine and its metabolites present simultaneously in the urine.

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