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Identification of Ca2+-Activated Neutral Protease in the Peripheral Nerve and Its Effects on Neurofilament Degeneration

โœ Scribed by Keiko Kamakura; Shoichi Ishiura; Hideo Sugita; Yasuo Toyokura

Book ID
111172397
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
731 KB
Volume
40
Category
Article
ISSN
0022-3042

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Calcium-Activated neutral protease in th
Calcium-Activated neutral protease in the peripheral nerve, which requires ฮผM order Ca2+, and its effect on the neurofilament triplet
โœ Dr. K. Kamakura; S. Ishiura; K. Suzuki; H. Sugita; Y. Toyokura ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 1010 KB

There are two types of calcium-activated neutral protease (CANP), m-CANP and p-CANP, following the nomenclature of Suzuki et a1 to show that each requires mM and pM Ca2+, respectively, for its activation. We found p-CANP activity in a crude CANP fraction extracted from the peripheral nerve, which de