✦ LIBER ✦

Identification of biologically active conformations in flexible drug molecules

✍ Scribed by R. H. Davies; D. A. Smith; D. J. McNeillie; T. R. Morris

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 863 KB
Volume: 16
Category: Article
ISSN: 0020-7608
DOI: 10.1002/qua.560160714

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Influence of conformational flexibility

Influence of conformational flexibility on biological activity in cyclic astin analogues

✍ Gabriella Saviano; Ettore Benedetti; Rosanna Cozzolino; Antonia De Capua; Paolo 📂 Article 📅 2004 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 174 KB

## Abstract The astins, a family of natural antitumor cyclopeptides, from the roots of Aster tataricus, consist of a 16‐membered ring system containing uncoded amino acid residues. The backbone conformation, with a cis‐3,4‐dichlorinated proline residue, plays an important role in antineoplastic act

Advances in Asymmetric Synthesis of Biol

Advances in Asymmetric Synthesis of Biologically Active Molecules Using Heterocycles as Building Blocks

✍ Pletro Spanu; Fausta Ulgheri 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 8 KB 👁 1 views

ChemInform Abstract: Zeolite H-BEA Catal

ChemInform Abstract: Zeolite H-BEA Catalyzed Multicomponent Reaction: One-Pot Synthesis of Amidoalkyl Naphthols — Biologically Active Drug-Like Molecules.

✍ Sunil R. Mistry; Rikesh S. Joshi; Kalpana C. Maheria 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 25 KB 👁 2 views

ChemInform Abstract: Identification of B

ChemInform Abstract: Identification of Biologically Active Sites in Laminin, an Extracellular Matrix Protein

✍ Motoyoshi Nomizu 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 1 views

Discovering Drugs Through Biological Tra

Discovering Drugs Through Biological Transformation: Role of Pharmacologically Active Metabolites in Drug Discovery

✍ Aberra Fura; Yue-Zhong Shu; Mingshe Zhu; Ronald L. Hanson; Vikram Roongta; Griff 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 7 KB

Conformational and topographical conside

Conformational and topographical considerations in the design of biologically active peptides

✍ Victor J. Hruby 📂 Article 📅 1993 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 833 KB