Identification of anti-idiotypic antibody in dogs
β Scribed by Kevin T. Schultz; Richard E.W. Halliwell
- Book ID
- 119099475
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 598 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0165-2427
No coin nor oath required. For personal study only.
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## Abstract We raised an antihuman thyrotropin antiβidiotypic antibody and showed that it was active at the thyrotropin receptor. Thus this antibody inhibited ^125^I bβTSH binding to thyroid plasma membranes, stimulated adenylate cyclase activity through a guanyl nucleotideβdependent mechanism, inc
Rabbit anti-rat anti-human thyrotropin anti-idiotypic antibodies have been raised. These antibodies were active at the thyrotropin (TSH) receptor, in that they inhibited 125I-labeled bovine TSH binding to thyroid plasma membranes, stimulated adenylate cyclase activity through a guanyl nucleotide-dep