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Identification of a novel human T-cell receptor Vβ subfamily by genomic cloning

✍ Scribed by Shan Wei; Patrick Concannon


Book ID
119145306
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
558 KB
Volume
41
Category
Article
ISSN
0198-8859

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Identification of novel human T-cell rec
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We have studied the diversity of the expressed human T-cell receptor (TCR) beta-chain repertoire by analysis of mRNA from unstimulated peripheral blood T-cells. The anchored-polymerase chain reaction (PCR) was used to isolate TCRB transcripts. Of 20 full or near full-length functional transcripts se