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Identification of a Novel Glutathione Conjugate of Flutamide in Incubations with Human Liver Microsomes

✍ Scribed by Kang, P.; Dalvie, D.; Smith, E.; Zhou, S.; Deese, A.

Book ID
118209149
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2007
Tongue
English
Weight
573 KB
Volume
35
Category
Article
ISSN
0090-9556

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## Abstract An assay based on microbore liquid chromatography–positive ion electrospray mass spectrometry with selected ion recording has been developed for the measurement of the glutathione conjugate of paracetamol (acetaminophen) in human hepatic microsomal incubations. A deuterated analogue of