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Identification of a new target molecule for a cascade therapy of polycystic kidney

✍ Scribed by Noriyuki Yoshida; Yoshihisa Yano; Atsushi Yoshiki; Munehisa Ueno; Nobuhiro Deguchi; Shinji Hirotsune

Book ID
111390329
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
932 KB
Volume
16
Category
Article
ISSN
0914-7470

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✍ Anna Banaszewska; Michal Piechota; Robert Plewa πŸ“‚ Article πŸ“… 2012 πŸ› SP Versita 🌐 English βš– 341 KB

## Abstract Proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a novel target for controlling plasma levels of low-density lipoprotein cholesterol (LDL-C) and decreasing the risk of cardiovascular diseases. At present it is clear that the major classes of commonly prescribed lipid