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Identification of a small molecule targeting annexin A7

โœ Scribed by Li, Haiying; Liu, Ning; Wang, Shengqing; Wang, Li; Zhao, Jing; Su, Le; Zhang, Yun; Zhang, Shangli; Xu, Zhigang; Zhao, Baoxiang; Miao, Junying


Book ID
123269936
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
1014 KB
Volume
1833
Category
Article
ISSN
0167-4889

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Identification of a novel small molecule
โœ Hye Jin Jung; Ki Hyun Kim; Nam Doo Kim; Gyoonhee Han; Ho Jeong Kwon ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 836 KB

Our recent study has shown that ubiquinol-cytochrome c reductase binding protein (UQCRB), the 13.4-kDa subunit of mitochondrial complex III, plays a crucial role in hypoxia-induced angiogenesis via mitochondrial reactive oxygen species (ROS)-mediated signaling. Here we report a new synthetic small m