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Identification of a new quantitative trait locus on Chromosome 7 controlling disease severity of collagen-induced arthritis in rats

✍ Scribed by Svetlana V. Dracheva; Elaine F. Remmers; Pércio S. Gulko; Yutaka Kawahito; Ryan E. Longman; Van R. Reese; Grant W. Cannon; Marie M. Griffiths; R. L. Wilder


Book ID
105948747
Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
74 KB
Volume
49
Category
Article
ISSN
0093-7711

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Objective. To identify novel non-major histocompatibility complex (non-MHC) genetic loci controlling the severity of homologous rat type I1 collagen-induced arthritis (CIA). Methods. We conducted a genome-wide scan to identify CLA regulatory quantitative trait loci (QTL) in an F, cross between DA (