Identification of a murine CD4+ T-lymphocyte response site in hepatitis C virus core protein
β Scribed by Ziping Chen; Ira Berkower; Wei-Mei Ching; R.Yuan-Hu Wang; Harvey J. Alter; J.Wai-kuo Shih
- Book ID
- 116097680
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 905 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0161-5890
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Cytotoxic T lymphocytes have been implicated in the control of hepatitis C virus (HCV) infection. Recognition by cytotoxic T lymphocytes of epitopes within HCV core protein has been defined previously by in vitro stimulation with synthetic peptides. The aim of this study has been to examine cytotoxi
## Abstract Prediction analysis of T~H~βcell epitopes in the VP3 capsid protein of the hepatitis A virus (HAV) revealed the occurrence of a putative T~H~ epitope in the 102β121 region complying with all the algorithms tested. To confirm these predictions, spleen T lymphocytes obtained from BALB/c m