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Identification of a deoxyguanosine-malondialdehyde adduct in rat and human urine

✍ Scribed by Sanjiv Agarwal; Jae Joon Wee; Mary Hadley; Harold H. Draper

Book ID
112774797
Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
468 KB
Volume
29
Category
Article
ISSN
0024-4201

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## Abstract The major adduct of malondialdehyde with guanine, M~1~G, was measured in human urine from non‐smoking healthy individuals. M~1~G is a mutagenic DNA lesion and a terminal product of lipid peroxidation __in vivo__ that may be implicated in cancer related to lifestyle and diet. On the basi