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Identification of 5-Methylcytosine in Complex Genomes

✍ Scribed by Hélène Thomassin; Edward J. Oakeley; Thierry Grange

Book ID
115639098
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
162 KB
Volume
19
Category
Article
ISSN
1046-2023

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✍ Geoffrey Grigg; Susan Clark 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 847 KB

To analyse the biologica1 role of 5-methylation of cytosine residues in DNA requires precise and efficient methods for detecting individua1 5-methylcytosines (5-MeCs) in genomic DNA. The methods developed over the past decade rely on either differential enzymatic or chemical cleavage of DNA, or more