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Identification of 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles as 5-HT2C receptor agonists

✍ Scribed by S. Röver; D.R. Adams; A. Bénardeau; J.M. Bentley; M.J. Bickerdike; A. Bourson; I.A. Cliffe; P. Coassolo; J.E.P. Davidson; C.T. Dourish; P. Hebeisen; G.A. Kennett; A.R. Knight; C.S. Malcolm; P. Mattei; A. Misra; J. Mizrahi; M. Muller; R.H.P. Porter; H. Richter; S. Taylor; S.P. Vickers

Book ID
108073685
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
179 KB
Volume
15
Category
Article
ISSN
0960-894X

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## Abstract A variety of novel 7‐sulfanylpyrazinoindole derivatives (V) (11 examples) is synthesized using a new and improved ring‐closing methodology for the assembly of the hexahydropyrazinol[1,2‐α]indole scaffold.