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Identification of 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles as new Pim kinase inhibitors

✍ Scribed by Suchaud, Virginie; Gavara, Laurent; Saugues, Emmanuelle; Nauton, Lionel; Théry, Vincent; Anizon, Fabrice; Moreau, Pascale

Book ID
120446129
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
954 KB
Volume
21
Category
Article
ISSN
0968-0896

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## Abstract New 4‐Aryl‐6‐methyl‐8‐phenyl‐2,3‐dihydropyrazolo[3,4‐__b__]diazepines and 4‐aryl‐8‐methyl‐6‐phenyl‐2,3‐dihydropyrazolo[4,3‐__b__]diazepines were obtained from the reaction of 4,5‐diamino‐3‐methyl‐1‐phenylpyrazole 1 with one equivalent of the 3‐dimethylaminopropiophenones 2 in absolute e