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Identification and Structure—Activity Relationships of Substituted Pyridones as Inhibitors of Pim-1 Kinase.

✍ Scribed by I. Wayne Cheney; Shunqi Yan; Todd Appleby; Heli Walker; Todd Vo; Nanhua Yao; Robert Hamatake; Zhi Hong; Jim Z. Wu

Publisher
John Wiley and Sons
Year
2007
Weight
23 KB
Volume
38
Category
Article
ISSN
0931-7597

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Synthesis and Structure-Activity Relationships of 2-Pyridones. Part 2. 8-(Fluoro-Substituted Pyrrolidinyl)-2-pyridones as Antibacterial Agents. -Various 2-pyridones, e.g. (III) and (V), are prepared in a previously reported manner and are investigated for their antibacterial activity. It is shown t