Active site mutants of the “non-hydrolyz
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Jomy Samuel; Martin E Tanner
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Article
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2004
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Elsevier Science
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English
⚖ 182 KB
The ''non-hydrolyzing'' bacterial UDP-N-acetylglucosamine 2-epimerase catalyzes the reversible interconversion of UDP-Nacetylglucosamine (UDP-GlcNAc) and UDP-N-acetylmannosamine (UDP-ManNAc). This homodimeric enzyme is allosterically activated by its substrate, UDP-GlcNAc, and it is thought that one