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Identification and determination of synthetic estrogens in pharmaceuticals by high-speed, reversed-phase partition chromatography

โœ Scribed by Robert W. Roos

Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
649 KB
Volume
63
Category
Article
ISSN
0022-3549

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Bromoisovalerylurea (bromvalerylurea) is a sedative-hypnotic given orally as a racemate. Enantiomers of this drug could be separated by high-performance liquid chromatography on the three chiral stationary phases (a vancomycin-bonded, b-cyclodextrin derivative-bonded, or urea derivative-bonded phase