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Identification and Characterization of a Novel Cell Cycle–Regulated Internal Ribosome Entry Site

✍ Scribed by Sigrid Cornelis; Yanik Bruynooghe; Geertrui Denecker; Sofie Van Huffel; Sandrine Tinton; Rudi Beyaert

Book ID
117736211
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
256 KB
Volume
5
Category
Article
ISSN
1097-2765

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Introduction of specific mutations into a synthetic internal ribosome entry site (IRES GTX ) derived from the GTX homeodomain protein revealed additional transcriptional activity. This novel synthetic P GTX promoter exhibited consensus core promoter modules such as the initiator (Inr) and the partia