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An internal ribosome entry site promotes translation of a novel SIV Pr55Gag isoform

✍ Scribed by Michael G. Nicholson; Sarah M. Rue; Janice E. Clements; Sheila A. Barber


Book ID
113946762
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
530 KB
Volume
349
Category
Article
ISSN
0042-6822

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Introduction of specific mutations into a synthetic internal ribosome entry site (IRES GTX ) derived from the GTX homeodomain protein revealed additional transcriptional activity. This novel synthetic P GTX promoter exhibited consensus core promoter modules such as the initiator (Inr) and the partia