CD1d-reactive NKT cells are required for the development of antigen-specific T regulatory (Tr) cells responsible for mediating systemic tolerance induced through an immune privileged site such as the eye. The aim of this study was to elucidate the cellular source of CD1d needed for NKT cell activati
✦ LIBER ✦
ICOS-dependent stimulation of NKT cells by marginal zone B cells
✍ Scribed by Natalia Zietara; Marcin Łyszkiewicz; Andreas Krueger; Siegfried Weiss
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 449 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0014-2980
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## Abstract The genetic changes in marginal zone B cell lymphomas (MZBCL) vary according to the anatomical region. This study aimed to investigate genomic aberrations in ocular MZBCL and to compare them with those of tumors from other anatomical sites. The study population comprised 24 cases of pri