ICE-related proteases in apoptosis
β Scribed by Atsushi Takahashi; William C. Earnshaw
- Book ID
- 117655248
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 720 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0959-437X
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π SIMILAR VOLUMES
The interleukin-1Β¬-converting enzyme (ICE) family of proteases is an important component of the mechanism of the apoptotic process, but the physiologic roles of the different homologs during apoptosis remain unclear. Significant information about the roles of proteolysis in apoptosis will be gained
Involvement of a unique family of cysteine proteases in the multistep apoptotic process has been documented. Cloning of several mammalian genes identifies some components of this cellular response. However, it is currently unclear which protease plays a role as a signal and/or effector of apoptosis.